ULK3 Protein, Active
| Catalog number: | B2019350 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 100 g |
| Molecular Weight or Concentration: | 62 kDa |
| Supplied as: | Resin |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | 70C |
| Keywords: | ULK3 Protein, Active |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
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- Goruppi S, Clocchiatti A, Bottoni G, Di Cicco E, Ma M, Tassone B, Neel V, Demehri S, Simon C, Paolo Dotto G. The ULK3 kinase is a determinant of keratinocyte self-renewal and tumorigenesis targeting the arginine methylome Nat Commun. 2023 Feb 16;14(1):887.
- Kasak L, Nks M, Eek P, Piirsoo A, Bhadoria R, Starkov P, Saarma M, Kasvandik S, Piirsoo M. Characterization of Protein Kinase ULK3 Regulation by Phosphorylation and Inhibition by Small Molecule SU6668 Biochemistry. 2018 Sep 18;57(37):5456-5465.
- Mathea S, Salah E, Tallant C, Chatterjee D, Berger BT, Konietzny R, Mller S, Kessler BM, Knapp S. Conformational plasticity of the ULK3 kinase domain Biochem J. 2021 Jul 30;478(14):2811-2823.
- Maloverjan A, Piirsoo M. Mammalian homologues of Drosophila fused kinase Vitam Horm. 2012;88:91-113.
- Gonzlez-Rodrguez P, Cheray M, Keane L, Engskog-Vlachos P, Joseph B. ULK3-dependent activation of GLI1 promotes DNMT3A expression upon autophagy induction Autophagy. 2022 Dec;18(12):2769-2780.
- Zhou M, Jiang J. Gli Phosphorylation Code in Hedgehog Signal Transduction Front Cell Dev Biol. 2022 Jan 25;10:846927.
- Jin Y, Zhao L, Zhang Y, Chen T, Shi H, Sun H, Ding S, Chen S, Cao H, Zhang G, Li Q, Gao J, Xiao M, Sheng C. BIN1 deficiency enhances ULK3-dependent autophagic flux and reduces dendritic size in mouse hippocampal neurons Autophagy. 2024 Sep 10:1-20.
- Maloverjan A, Piirsoo M, Kasak L, Peil L, sterlund T, Kogerman P. Dual function of UNC-51-like kinase 3 (Ulk3) in the Sonic hedgehog signaling pathway J Biol Chem. 2010 Sep 24;285(39):30079-90.
