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Tacrolimus Antibody Conjugated to ABEI

Original price was: $116.80.Current price is: $70.46.

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SKU: PW14836861098 Category:

Tacrolimus Antibody Conjugated to ABEI

Catalog number: B2010727
Lot number: Batch Dependent
Expiration date: Batch Dependent
Amount: 50 g
Concentration: 1 mg/mL
Supplied as: Liquid
Storage: 20C
Keywords: Tacrolimus MAB ABEI, FK506 antibody ABEI
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 Mcm) and are filtered through 0.22 m.

Tacrolimus Antibody Conjugated to ABEI is a chemiluminescent reagent designed for high-sensitivity detection of tacrolimus (FK506) in clinical and research settings. This product features a monoclonal antibody specific to tacrolimus, conjugated to ABEI (N-(4-Aminobutyl)-N-ethylisoluminol), a luminol derivative known for its stable and intense light emission. Supplied at 1 mg/mL in liquid format, this conjugate is optimized for use in CLIA platforms and therapeutic drug monitoring workflows.

Tacrolimus is a potent immunosuppressant used in organ transplantation and autoimmune disease management. The ABEI label enables sensitive detection in chemiluminescent immunoassays, allowing researchers and clinicians to quantify tacrolimus levels with precision and reproducibility. This reagent is particularly useful in pharmacokinetic studies, toxicity profiling, and assay development for transplant monitoring.

The antibody-ABEI conjugate offers high specificity, low background, and compatibility with manual and automated platforms. It is formulated in ultrapure water and filtered through 0.22 m membranes to ensure purity and consistency. Applications include CLIA assay development, tacrolimus pharmacology research, and biomarker discovery in dermatology, hepatology, and nephrology.

Key benefits:

  • Monoclonal antibody conjugated to ABEI for chemiluminescent detection of tacrolimus
  • Supports CLIA assay development and therapeutic drug monitoring
  • High specificity and low background signal in complex matrices
  • Biotechnology grade; filtered through 0.22 m membranes
  • Supplied at 1 mg/mL; store at 20C to maintain activity

Products are for in vitro research use only (RUO).

References

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  • Spencer CM et al. Clinical efficacy of tacrolimus in transplantation. Drugs. 1997 Dec;54(6):925975.
  • Haroon N et al. Tacrolimus toxicity with minimal symptoms. Am J Ther. 2016 MarApr;23(2):e631634.
  • Truneka P. Once-daily tacrolimus in liver transplantation. Curr Opin Organ Transplant. 2017 Apr;22(2):118122.
  • Posadas Salas MA et al. Clinical utility of once-daily tacrolimus. Drug Des Devel Ther. 2014 Sep 1;8:11831194.
  • Pustisek N et al. Tacrolimus ointment for atopic dermatitis. Acta Dermatovenerol Croat. 2002 Mar;10(1):2532.
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  • Huppertz A et al. Food effects on tacrolimus formulations. Clin Pharmacol Drug Dev. 2021 Aug;10(8):899907.
  • Rallis E et al. New roles for topical tacrolimus. Expert Opin Investig Drugs. 2007 Aug;16(8):12671276.