Recombinant UBE2H Protein
| Catalog number: | B2017763 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 50 g |
| Molecular Weight or Concentration: | 22.82 kDa |
| Supplied as: | Solution |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | -80C |
| Keywords: | Ubiquitin conjugating enzyme E2 H, ubiquitin carrier protein H, E2-20K, GID3, UBC8, UBCH, UBCH2 |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Rajendra R, Malegaonkar D, Pungaliya P, Marshall H, Rasheed Z, Brownell J, Liu LF, Lutzker S, Saleem A, Rubin EH. Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53 J Biol Chem. 2004 Aug 27;279(35):36440-4.
- Kaiser P, Mandl S, Schweiger M, Schneider R. Characterization of functionally independent domains in the human ubiquitin conjugating enzyme UbcH2 FEBS Lett. 1995 Dec 18;377(2):193-6.
- Chrustowicz J, Sherpa D, Li J, Langlois CR, Papadopoulou EC, Vu DT, Hehl LA, Karayel , Beier V, von Gronau S, Mller J, Prabu JR, Mann M, Kleiger G, Alpi AF, Schulman BA. Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies Mol Cell. 2024 Jan 18;84(2):293-308.e14.
- Sherpa D, Mueller J, Karayel , Xu P, Yao Y, Chrustowicz J, Gottemukkala KV, Baumann C, Gross A, Czarnecki O, Zhang W, Gu J, Nilvebrant J, Sidhu SS, Murray PJ, Mann M, Weiss MJ, Schulman BA, Alpi AF. Modular UBE2H-CTLH E2-E3 complexes regulate erythroid maturation Elife. 2022 Dec 2;11:e77937.
- Kumari S, Kumar P. Identification and characterization of putative biomarkers and therapeutic axis in Glioblastoma multiforme microenvironment Front Cell Dev Biol. 2023 Jul 19;11:1236271.
- Shin U, Choi Y, Ko HS, Myung K, Lee S, Cheon CK, Lee Y. A heterozygous mutation in UBE2H in a patient with developmental delay leads to an aberrant brain development in zebrafish Hum Genomics. 2023 May 19;17(1):44.
- Zhang H, Cui Z, Cheng D, Du Y, Guo X, Gao R, Chen J, Sun W, He R, Ma X, Peng Q, Martin BN, Yan W, Rong Y, Wang C. RNF186 regulates EFNB1 (ephrin B1)-EPHB2-induced autophagy in the colonic epithelial cells for the maintenance of intestinal homeostasis Autophagy. 2021 Oct;17(10):3030-3047.
- Lim KH, Joo JY. Predictive Potential of Circulating Ube2h mRNA as an E2 Ubiquitin-Conjugating Enzyme for Diagnosis or Treatment of Alzheimers Disease Int J Mol Sci. 2020 May 11;21(9):3398.
- Guo X, Ma A, Huang Z, Wang XA, Yang K, Liu Z, Zhang J, Cui W. Molecular characterization of ubiquitin-conjugating enzyme gene ube2h and siRNA-mediated regulation on targeting p53 in turbot, Scophthalmus maximus J Therm Biol. 2021 Jul;99:102938.
