Recombinant Mouse Siglec-2/CD22 Protein
| Catalog number: | B2019191 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 50 g |
| Molecular Weight or Concentration: | 78.8 kDa |
| Supplied as: | Powder |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | -20C |
| Keywords: | A530093D23 Protein, Mouse; Cd22 Protein, Mouse; Lyb-8 Protein, Mouse; Lyb8 Protein, Mouse; Siglec2 Protein, Mouse |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
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- Vallera DA, Todhunter DA, Kuroki DW, Shu Y, Sicheneder A, Chen H. A bispecific recombinant immunotoxin, DT2219, targeting human CD19 and CD22 receptors in a mouse xenograft model of B-cell leukemia/lymphoma Clin Cancer Res. 2005 May 15;11(10):3879-88.
- Nikolova KA, Mihaylova NM, Voynova EN, Tchorbanov AI, Voll RE, Vassilev TL. Selective silencing of autoreactive B lymphocytes-Following the Natures way Autoimmun Rev. 2010 Sep;9(11):775-9.
- Sathish JG, Walters J, Luo JC, Johnson KG, Leroy FG, Brennan P, Kim KP, Gygi SP, Neel BG, Matthews RJ. CD22 is a functional ligand for SH2 domain-containing protein-tyrosine phosphatase-1 in primary T cells J Biol Chem. 2004 Nov 12;279(46):47783-91.
- Haso W, Lee DW, Shah NN, Stetler-Stevenson M, Yuan CM, Pastan IH, Dimitrov DS, Morgan RA, FitzGerald DJ, Barrett DM, Wayne AS, Mackall CL, Orentas RJ. Anti-CD22-chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia Blood. 2013 Feb 14;121(7):1165-74.
- Cao A, Alluqmani N, Buhari FHM, Wasim L, Smith LK, Quaile AT, Shannon M, Hakim Z, Furmli H, Owen DM, Savchenko A, Treanor B. Galectin-9 binds IgM-BCR to regulate B cell signaling Nat Commun. 2018 Aug 17;9(1):3288.
- Newton DL, Stockwin LH, Rybak SM. Anti-CD22 Onconase: preparation and characterization Methods Mol Biol. 2009;525:425-43, xiv.
- Toda M, Akita K, Inoue M, Taketani S, Nakada H. Down-modulation of B cell signal transduction by ligation of mucins to CD22 Biochem Biophys Res Commun. 2008 Jul 18;372(1):45-50.
- John B, Herrin BR, Raman C, Wang YN, Bobbitt KR, Brody BA, Justement LB. The B cell coreceptor CD22 associates with AP50, a clathrin-coated pit adapter protein, via tyrosine-dependent interaction J Immunol. 2003 Apr 1;170(7):3534-43.
