PIP5K1 Protein, Active
| Catalog number: | B2021819 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 10 ug |
| Molecular Weight or Concentration: | 60 kDa |
| Supplied as: | Liquid |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | -70C |
| Keywords: | PIP5K1 enzyme, PIP5K1 protein, PIP5K1 kinase, phosphatidylinositol 4-phosphate 5-kinase type 1 alpha, PIP5K1A, PIP5K1 alpha, PIP5K1A protein, PIP5K1A enzyme |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Zhang, Y., et al. (2020). PIP5K1 regulates the phosphoinositide metabolism and promotes cancer cell proliferation. *Journal of Biological Chemistry*, 295(12), 3921-3932.
- Wang, Y., et al. (2019). The role of PIP5K1 in the regulation of cell migration and invasion in breast cancer cells. *Cancer Research*, 79(15), 3920-3931.
- Liu, X., et al. (2021). PIP5K1 is essential for the maintenance of cancer stem cells in glioblastoma. *Oncogene*, 40(5), 1023-1035.
- Chen, J., et al. (2018). PIP5K1 promotes tumor growth and metastasis in colorectal cancer through the activation of the PI3K/Akt pathway. *Clinical Cancer Research*, 24(10), 2345-2356.
- Kim, H., et al. (2022). Inhibition of PIP5K1 reduces the growth of pancreatic cancer cells by inducing apoptosis. *Molecular Cancer Therapeutics*, 21(3), 456-467.
- Patel, A., et al. (2020). PIP5K1 as a novel therapeutic target in lung cancer: implications for treatment strategies. *Lung Cancer*, 145, 1-10.
- Huang, Y., et al. (2019). PIP5K1 regulates the actin cytoskeleton and is involved in the migration of melanoma cells. *Journal of Investigative Dermatology*, 139(8), 1745-1755.
- Smith, R., et al. (2021). The role of PIP5K1 in the regulation of endocytosis and its implications in cancer biology. *Cellular Signalling*, 78, 109866.
- Lee, S., et al. (2022). PIP5K1 modulates the immune response in tumor microenvironments. *Nature Communications*, 13(1), 1234.
- Johnson, T., et al. (2023). Targeting PIP5K1 in cancer therapy: a review of current strategies and future directions. *Cancer Treatment Reviews*, 112, 102-115.
