Phospho-CrkL (Tyr207) Rabbit PE Conjugate
| Catalog number: | B2018892 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 10 ug |
| Molecular Weight or Concentration: | 33.78 kDa |
| Supplied as: | Solution |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | 2-8 |
| Keywords: | Crk-like protein; CRKL; v-crk sarcoma virus CT10 oncogene homolog (avian)-like |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Kumar S, Stainer A, Dubrulle J, Simpkins C, Cooper JA. Cas phosphorylation regulates focal adhesion assembly Elife. 2023 Jul 25;12:e90234.
- Estrada A 3rd, Rodriguez AC, Rodriguez G, Grant AH, Ayala-Marin YM, Arrieta AJ, Kirken RA. Phosphorylation of CrkL S114 induced by common gamma chain cytokines and T-cell receptor signal transduction Sci Rep. 2021 Aug 20;11(1):16951.
- La Rose P, Holm-Eriksen S, Konig H, Hrtel N, Ernst T, Debatin J, Mueller MC, Erben P, Binckebanck A, Wunderle L, Shou Y, Dugan M, Hehlmann R, Ottmann OG, Hochhaus A. Phospho-CRKL monitoring for the assessment of BCR-ABL activity in imatinib-resistant chronic myeloid leukemia or Ph+ acute lymphoblastic leukemia patients treated with nilotinib Haematologica. 2008 May;93(5):765-9.
- Scopim-Ribeiro R, Machado-Neto JA, Eide CA, Coelho-Silva JL, Fenerich BA, Fernandes JC, Scheucher PS, Savage Stevens SL, de Melo Campos P, Olalla Saad ST, de Carvalho Palma L, de Figueiredo-Pontes LL, Simes BP, Rego EM, Tognon CE, Druker BJ, Traina F. NT157, an IGF1R-IRS1/2 inhibitor, exhibits antineoplastic effects in pre-clinical models of chronic myeloid leukemia Invest New Drugs. 2021 Jun;39(3):736-746.
- Kong Y, Wu YL, Song Y, Shi MM, Cao XN, Zhao HY, Qin YZ, Lai YY, Jiang H, Jiang Q, Huang XJ. Ruxolitinib/nilotinib cotreatment inhibits leukemia-propagating cells in Philadelphia chromosome-positive ALL J Transl Med. 2017 Aug 30;15(1):184.
- Lago SG, Tomasik J, van Rees GF, Rustogi N, Vzquez-Bourgon J, Papiol S, Suarez-Pinilla P, Crespo-Facorro B, Bahn S. Peripheral lymphocyte signaling pathway deficiencies predict treatment response in first-onset drug-nave schizophrenia Brain Behav Immun. 2022 Jul;103:37-49.
- Luo FR, Yang Z, Camuso A, Smykla R, McGlinchey K, Fager K, Flefleh C, Castaneda S, Inigo I, Kan D, Wen ML, Kramer R, Blackwood-Chirchir A, Lee FY. Dasatinib (BMS-354825) pharmacokinetics and pharmacodynamic biomarkers in animal models predict optimal clinical exposure Clin Cancer Res. 2006 Dec 1;12(23):7180-6.
- Dong G, Kalifa R, Nath PR, Gelkop S, Isakov N. TCR crosslinking promotes Crk adaptor protein binding to tyrosine-phosphorylated CD3 chain Biochem Biophys Res Commun. 2017 Jul 1;488(3):541-546.
- Shigeno-Nakazawa Y, Kasai T, Ki S, Kostyanovskaya E, Pawlak J, Yamagishi J, Okimoto N, Taiji M, Okada M, Westbrook J, Satta Y, Kigawa T, Imamoto A. A pre-metazoan origin of the CRK gene family and co-opted signaling network Sci Rep. 2016 Sep 30;6:34349.
