PEGylated Urate Oxidase Enzyme
| Catalog number: | B2013079 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 100 U |
| Molecular Weight or Concentration: | N/A |
| Supplied as: | Lyophilized Powder |
| Applications: | molecular tool for various biochemical applications |
| Storage: | -20C |
| Keywords: | PEGylated urate oxidase enzyme |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Pegloticase 2021 Aug 16. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006.
- Schlesinger N, Lipsky PE. Pegloticase treatment of chronic refractory gout: Update on efficacy and safety Semin Arthritis Rheum. 2020 Jun;50(3S):S31-S38.
- Pegloticase 2018 May 21. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012.
- Padda IS, Bhatt R, Parmar M. Pegloticase 2022 Nov 30. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan.
- Dean L, Kane M. Pegloticase Therapy and G6PD Genotype 2020 Oct 1. In: Pratt VM, Scott SA, Pirmohamed M, Esquivel B, Kattman BL, Malheiro AJ, editors. Medical Genetics Summaries [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2012.
- Botson JK, Tesser JRP, Bennett R, Kenney HM, Peloso PM, Obermeyer K, LaMoreaux B, Weinblatt ME, Peterson J. Pegloticase in Combination With Methotrexate in Patients With Uncontrolled Gout: A Multicenter, Open-label Study (MIRROR) J Rheumatol. 2021 May;48(5):767-774.
- Anderson A, Singh JA. Pegloticase for chronic gout Cochrane Database Syst Rev. 2010 Mar 17;2010(3):CD008335.
- Sundy JS, Baraf HS, Yood RA, Edwards NL, Gutierrez-Urena SR, Treadwell EL, Vzquez-Mellado J, White WB, Lipsky PE, Horowitz Z, Huang W, Maroli AN, Waltrip RW 2nd, Hamburger SA, Becker MA. Efficacy and tolerability of pegloticase for the treatment of chronic gout in patients refractory to conventional treatment: two randomized controlled trials JAMA. 2011 Aug 17;306(7):711-20.
- Shannon JA, Cole SW. Pegloticase: a novel agent for treatment-refractory gout Ann Pharmacother. 2012 Mar;46(3):368-76.
