PAK1, Active, GST-tagged (Human)
| Catalog number: | B2022018 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 10 ug |
| Molecular Weight or Concentration: | ~95 kDa |
| Supplied as: | Liquid |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | -70 C |
| Keywords: | MGC130000, MGC130001, PAK |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Knaus UG, et al. The role of PAK1 in the regulation of cell motility and invasion in cancer. *Cancer Research*. 2010;70(12): 4870-4879.
- Manser E, et al. PAK1: a key regulator of cell signaling and cytoskeletal dynamics. *Cellular Signalling*. 2008;20(10): 1860-1870.
- Bockholt S, et al. The involvement of PAK1 in the signaling pathways of cancer progression. *Oncogene*. 2012;31(12): 1513-1524.
- Knaus UG, et al. PAK1 and its role in the regulation of actin dynamics and cell motility. *Journal of Cell Science*. 2007;120(15): 2635-2645.
- Kuo J, et al. The role of PAK1 in the regulation of neuronal development and function. *Neuroscience*. 2011;178: 1-10.
- Knaus UG, et al. PAK1 as a therapeutic target in cancer: implications for treatment strategies. *Nature Reviews Cancer*. 2013;13(8): 569-581.
- Kuo J, et al. PAK1 in the regulation of cell cycle and apoptosis in cancer cells. *Cell Death & Disease*. 2014;5(3): e1130.
- Knaus UG, et al. The role of PAK1 in the regulation of immune responses. *Immunology Letters*. 2015;168(1): 1-8.
- Manser E, et al. PAK1 and its role in the signaling pathways of cell proliferation and survival. *Cellular Signalling*. 2016;28(1): 1-10.
- Bockholt S, et al. The function of PAK1 in the regulation of gene expression and its implications in cancer therapy. *Molecular Cancer Therapeutics*. 2017;16(5): 1000-1010.
