O-GlcNAcase Enzyme
| Catalog number: | B2019345 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 1,000 units |
| Molecular Weight or Concentration: | N/A |
| Supplied as: | Powder |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | RT |
| Keywords: | O-GlcNAcase Enzyme |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Yang X, Qian K. Protein O-GlcNAcylation: emerging mechanisms and functions Nat Rev Mol Cell Biol. 2017 Jul;18(7):452-465.
- Lu P, Liu Y, He M, Cao T, Yang M, Qi S, Yu H, Gao H. Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex Nat Commun. 2023 Oct 31;14(1):6952.
- Chang YH, Weng CL, Lin KI. O-GlcNAcylation and its role in the immune system J Biomed Sci. 2020 Apr 29;27(1):57.
- Elbatrawy AA, Kim EJ, Nam G. O-GlcNAcase: Emerging Mechanism, Substrate Recognition and Small-Molecule Inhibitors ChemMedChem. 2020 Jul 20;15(14):1244-1257.
- Nagel AK, Ball LE. O-GlcNAc transferase and O-GlcNAcase: achieving target substrate specificity Amino Acids. 2014 Oct;46(10):2305-16.
- Alonso J, Schimpl M, van Aalten DM. O-GlcNAcase: promiscuous hexosaminidase or key regulator of O-GlcNAc signaling? J Biol Chem. 2014 Dec 12;289(50):34433-9.
- Wani WY, Chatham JC, Darley-Usmar V, McMahon LL, Zhang J. O-GlcNAcylation and neurodegeneration Brain Res Bull. 2017 Jul;133:80-87.
- Costa TJ, Wilson EW, Fontes MT, Pernomian L, Tostes RC, Wenceslau CF, McCarthy CG. The O-GlcNAc dichotomy: when does adaptation become pathological? Clin Sci (Lond). 2023 Nov 29;137(22):1683-1697.
- Borodkin VS, Rafie K, Selvan N, Aristotelous T, Navratilova I, Ferenbach AT, van Aalten DMF. O-GlcNAcase Fragment Discovery with Fluorescence Polarimetry ACS Chem Biol. 2018 May 18;13(5):1353-1360.
