Neutravidin Magnetic Beads (High Specificity)

Neutravidin Magnetic Beads (High Specificity) Catalog M2010003 (1 mL)

Premium Neutravidin-coated magnetic beads engineered for ultra-specific, high-capacity biotin capture in complex assays. Neutravidin Magnetic Beads (High Specificity) (Catalog M2010003, 1 mL) offer a robust and reliable platform for isolating biotin-labeled molecules with exceptional purity. Featuring a uniform 0.91.1 m superparamagnetic bead coated with Neutravidin, these beads deliver unmatched binding capacityexceeding 3500 pmol biotin per mgand minimal non-specific interactions.

The iron oxide core (approx. 61% magnetite) ensures rapid magnetic responsiveness and efficient bead recovery protocols. Highly stable with no ligand leaching, this formulation supports advanced molecular workflows: from antigen and antibody capture to nucleic acid purification under stringent conditions. Researchers in immunodiagnostics, proteomics, diagnostics, and beyond benefit from the high specificity and reproducibility across experimental conditions.

Shipped as a ready-to-use liquid suspension and stored at 28 C (never frozen), these beads integrate seamlessly into automated systems and high-throughput assays. Bulk order options are available for high-volume usage. As with all offerings in our portfolio, this product is designated for Research Use Only (RUO).

Why scientists choose this product:

• Neutravidin coating ensures ultra-low non-specific binding
• High biotin-binding capacity (>3500 pmol/mg) maximizes capture efficiency
• Uniform 0.91.1 m bead size promotes reproducibility in automated assays
• Stable formulation prevents leaching and ensures long-term usability
• Ideal for immunocapture, molecular purification, and high-sensitivity workflows

Indication for Use:
This product is for Research Use Only (RUO). It is not intended for diagnostic, therapeutic, or clinical applications.

References:

• 1: Lapitan LDS , Xu Y , Guo Y , Zhou D . Combining magnetic nanoparticle capture and poly-enzyme nanobead amplification for ultrasensitive detection and discrimination of DNA single nucleotide polymorphisms. Nanoscale. 2019 Jan 17;11(3):1195-1204.
• 2: Salvador M , Gallo-Cordova , Moyano A , Martnez-Garca JC , Blanco-Lpez MC , Puerto Morales M , Rivas M . Improved magnetic lateral flow assays with optimized nanotags for point-of-use inductive biosensing. Analyst. 2020 Aug 24;145(17):5905-5914.
• 3: Moyano A, Serrano-Pertierra E, Salvador M, Martnez-Garca JC, Pieiro Y, Yaez-Vilar S, Gnzalez-Gmez M, Rivas J, Rivas M, Blanco-Lpez MC. Carbon- Coated Superparamagnetic Nanoflowers for Biosensors Based on Lateral Flow Immunoassays. Biosensors (Basel). 2020 Jul 22;10(8):80.
• 4: Arvalo B, Serafn V, Snchez-Paniagua M, Montero-Calle A, Barderas R, Lpez- Ruz B, Campuzano S, Yez-Sedeo P, Pingarrn JM. Fast and sensitive diagnosis of autoimmune disorders through amperometric biosensing of serum anti-dsDNA autoantibodies. Biosens Bioelectron. 2020 Jul 15;160:112233.
• 5: Guerrero S , Snchez-Tirado E , Martnez-Garca G , Gonzlez-Corts A , Yez-Sedeo P , Pingarrn JM . Electrochemical biosensor for the simultaneous determination of rheumatoid factor and anti-cyclic citrullinated peptide antibodies in human serum. Analyst. 2020 Jul 7;145(13):4680-4687.
• 6: Muoz-San Martn C, Pedrero M, Gamella M, Montero-Calle A, Barderas R, Campuzano S, Pingarrn JM. A novel peptide-based electrochemical biosensor for the determination of a metastasis-linked protease in pancreatic cancer cells. Anal Bioanal Chem. 2020 Sep;412(24):6177-6188.
• 7: Lapitan LDS Jr, Zhou D. A simple magnetic nanoparticle-poly-enzyme nanobead sandwich assay for direct, ultrasensitive DNA detection. Methods Enzymol. 2020;630:453-480.
• 8: Gandhi S, Arami H, Krishnan KM. Detection of Cancer-Specific Proteases Using Magnetic Relaxation of Peptide-Conjugated Nanoparticles in Biological Environment. Nano Lett. 2016 Jun 8;16(6):3668-74.
• 9: Salvador M, Gutirrez G, Noriega S, Moyano A, Blanco-Lpez MC, Matos M. Microemulsion Synthesis of Superparamagnetic Nanoparticles for Bioapplications. Int J Mol Sci. 2021 Jan 4;22(1):427.
• 10: Ryu Y, Jin Z, Lee JJ, Noh SH, Shin TH, Jo SM, Choi J, Park H, Cheon J, Kim HS. Size-controlled construction of magnetic nanoparticle clusters using DNA- binding zinc finger protein. Angew Chem Int Ed Engl. 2015 Jan 12;54(3):923-6.