Human JAK3 Protein Active
| Catalog number: | B2014187 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 10 g |
| Molecular Weight or Concentration: | 39.9 kDa |
| Supplied as: | Solution |
| Applications: | molecular tool for various biochemical applications |
| Storage: | -20C |
| Keywords: | JAK3 Protein |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Zhang H, Watanabe R, Berry GJ, Tian L, Goronzy JJ, Weyand CM. Inhibition of JAK-STAT Signaling Suppresses Pathogenic Immune Responses in Medium and Large Vessel Vasculitis Circulation. 2018 May 1;137(18):1934-1948.
- Tefferi A. JAK and MPL mutations in myeloid malignancies Leuk Lymphoma. 2008 Mar;49(3):388-97.
- Li HP, Chang YS. Epstein-Barr virus latent membrane protein 1: structure and functions J Biomed Sci. 2003 Sep-Oct;10(5):490-504.
- Lin J, Zhang Y, Wang M, Zhang Y, Li P, Cao Y, Yang X. Therapeutic Effects of Tofacitinib on Pristane-Induced Murine Lupus Arch Rheumatol. 2022 Mar 3;37(2):195-204.
- Strand V, Ahadieh S, French J, Geier J, Krishnaswami S, Menon S, Checchio T, Tensfeldt TG, Hoffman E, Riese R, Boy M, G_mez-Reino JJ. Systematic review and meta-analysis of serious infections with tofacitinib and biologic disease-modifying antirheumatic drug treatment in rheumatoid arthritis clinical trials Arthritis Res Ther. 2015 Dec 15;17:362.
- Chi F, Chen L, Wang C, Li L, Sun X, Xu Y, Ma T, Liu K, Ma X, Shu X. JAK3 inhibitors based on thieno[3,2-d]pyrimidine scaffold: design, synthesis and bioactivity evaluation for the treatment of B-cell lymphoma Bioorg Chem. 2020 Jan;95:103542.
- Cheng YL, Zhang XH, Sun YW, Wang WJ, Huang J, Chu NL, Fang SP, Wu ZK. Genomewide DNA Methylation Responses in Patients with _-Thalassemia Treated with Yisui Shengxue Granules () Chin J Integr Med. 2019 Jul;25(7):490-496.
- Sanachai K, Mahalapbutr P, Tabtimmai L, Seetaha S, Kaekratoke N, Chamni S, Azam SS, Choowongkomon K, Rungrotmongkol T. In Silico and In Vitro Study of Janus Kinases Inhibitors from Naphthoquinones Molecules. 2023 Jan 6;28(2):597.
- y_yska-Granica B, Trzaskowski B, Dutkiewicz M, Zegrocka-Stendel O, Machciska M, Bocian K, Kowalewska M, Koziak K. The anti-inflammatory potential of cefazolin as common gamma chain cytokine inhibitor Sci Rep. 2020 Feb 19;10(1):2886.








