Human CDK1 Protein
| Catalog number: | B2011904 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 100 g |
| Molecular Weight or Concentration: | 1 mg/mL |
| Supplied as: | Solution |
| Applications: | molecular tool for various biochemical applications |
| Storage: | -20 C |
| Keywords: | Cyclin-dependent kinase 1 isoform 1 protein, CDC2 protein, CDC28A protein, P34CDC2 protein |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Haneke K, Schott J, Lindner D, Hollensen AK, Damgaard CK, Mongis C, Knop M, Palm W, Ruggieri A, Stoecklin G. CDK1 couples proliferation with protein synthesis J Cell Biol. 2020 Mar 2;219(3):e201906147.
- Yu J, Raia P, Ghent CM, Raisch T, Sadian Y, Cavadini S, Sabale PM, Barford D, Raunser S, Morgan DO, Boland A. Structural basis of human separase regulation by securin and CDK1-cyclin B1 Nature. 2021 Aug;596(7870):138-142.
- Xie B, Wang S, Jiang N, Li JJ. Cyclin B1/CDK1-regulated mitochondrial bioenergetics in cell cycle progression and tumor resistance Cancer Lett. 2019 Feb 28;443:56-66.
- Schmidt M, Rohe A, Platzer C, Najjar A, Erdmann F, Sippl W. Regulation of G2/M Transition by Inhibition of WEE1 and PKMYT1 Kinases Molecules. 2017 Nov 23;22(12):2045.
- Li Q, Zhou D, Jia F, Zhang L, Ashraf U, Li Y, Duan H, Song Y, Chen H, Cao S, Ye J. Japanese Encephalitis Virus NS1 Protein Interacts with Host CDK1 Protein to Regulate Antiviral Response Microbiol Spectr. 2021 Dec 22;9(3):e0166121.
- Singh P, Pesenti ME, Maffini S, Carmignani S, Hedtfeld M, Petrovic A, Srinivasamani A, Bange T, Musacchio A. BUB1 and CENP-U, Primed by CDK1, Are the Main PLK1 Kinetochore Receptors in Mitosis Mol Cell. 2021 Jan 7;81(1):67-87.e9.
- Wu CX, Wang XQ, Chok SH, Man K, Tsang SHY, Chan ACY, Ma KW, Xia W, Cheung TT. Blocking CDK1/PDK1/-Catenin signaling by CDK1 inhibitor RO3306 increased the efficacy of sorafenib treatment by targeting cancer stem cells in a preclinical model of hepatocellular carcinoma Theranostics. 2018 Jun 13;8(14):3737-3750.
- Zhang P, Kawakami H, Liu W, Zeng X, Strebhardt K, Tao K, Huang S, Sinicrope FA. Targeting CDK1 and MEK/ERK Overcomes Apoptotic Resistance in BRAF-Mutant Human Colorectal Cancer Mol Cancer Res. 2018 Mar;16(3):378-389.
- Crncec A, Hochegger H. Triggering mitosis FEBS Lett. 2019 Oct;593(20):2868-2888.
