Human ALAD Protein (Highly Pure)
| Catalog number: | B2011571 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 50 g |
| Molecular Weight or Concentration: | 1 mg/mL |
| Supplied as: | Solution |
| Applications: | molecular tool for various biochemical applications |
| Storage: | -20 C |
| Keywords: | ALAD protein (His tag), PBGS protein, ALADH protein, Delta-aminolevulinic acid dehydratase protein |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Jaffe EK. Porphobilinogen synthase: An equilibrium of different assemblies in human health Prog Mol Biol Transl Sci. 2020;169:85-104.
- Qader A, Rehman K, Akash MSH. Genetic susceptibility of -ALAD associated with lead (Pb) intoxication: sources of exposure, preventive measures, and treatment interventions Environ Sci Pollut Res Int. 2021 Sep;28(33):44818-44832.
- Schmitt SM, Neslund-Dudas C, Shen M, Cui C, Mitra B, Dou QP. Involvement of ALAD-20S Proteasome Complexes in Ubiquitination and Acetylation of Proteasomal 2 Subunits J Cell Biochem. 2016 Jan;117(1):144-51.
- Bergdahl IA, Grubb A, Schtz A, Desnick RJ, Wetmur JG, Sassa S, Skerfving S. Lead binding to delta-aminolevulinic acid dehydratase (ALAD) in human erythrocytes Pharmacol Toxicol. 1997 Oct;81(4):153-8.
- Andrei Nogara P, Batista Teixeira Rocha J. In Silico Studies of Mammalian -ALAD Interactions with Selenides and Selenoxides Mol Inform. 2018 Apr;37(4):e1700091.
- Liu G, Sil D, Maio N, Tong WH, Bollinger JM Jr, Krebs C, Rouault TA. Heme biosynthesis depends on previously unrecognized acquisition of iron-sulfur cofactors in human amino-levulinic acid dehydratase Nat Commun. 2020 Dec 9;11(1):6310.
- Kelada SN, Shelton E, Kaufmann RB, Khoury MJ. Delta-aminolevulinic acid dehydratase genotype and lead toxicity: a HuGE review Am J Epidemiol. 2001 Jul 1;154(1):1-13.
- Gonick HC. Lead-binding proteins: a review J Toxicol. 2011;2011:686050.
- Jaffe EK, Stith L. ALAD porphyria is a conformational disease Am J Hum Genet. 2007 Feb;80(2):329-37.
