Human Adenine Phosphoribosyltransferase (APRT)
| Catalog number: | B2015619 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 10 ug |
| Molecular Weight or Concentration: | 19.6 kDa (180 aa) |
| Supplied as: | Solution |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | -20C |
| Keywords: | AMP, APRTD, AMP diphosphorylase, Transphosphoribosidase |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Edvardsson VO, Sahota A, Palsson R. Adenine Phosphoribosyltransferase Deficiency 2012 Aug 30 [updated 2019 Sep 26]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews() [Internet]. Seattle (WA): University of Washington, Seattle; 19932024.
- Bolle G, Harambat J, Bensman A, Knebelmann B, Daudon M, Ceballos-Picot I. Adenine phosphoribosyltransferase deficiency Clin J Am Soc Nephrol. 2012 Sep;7(9):1521-7.
- Young GH, Lin JT, Cheng YF, Ho CF, Kuok QY, Hsu RC, Liao WR, Chen CC, Chen HM. Modulation of adenine phosphoribosyltransferase-mediated salvage pathway to accelerate diabetic wound healing FASEB J. 2021 Mar;35(3):e21296.
- Silva CH, Silva M, Iulek J, Thiemann OH. Structural complexes of human adenine phosphoribosyltransferase reveal novel features of the APRT catalytic mechanism J Biomol Struct Dyn. 2008 Jun;25(6):589-97.
- Fratini A, Simmers RN, Callen DF, Hyland VJ, Tischfield JA, Stambrook PJ, Sutherland GR. A new location for the human adenine phosphoribosyltransferase gene (APRT) distal to the haptoglobin (HP) and fra(16)(q23)(FRA16D) loci Cytogenet Cell Genet. 1986;43(1-2):10-3.
- Glockzin K, Meek TD, Katzfuss A. Characterization of adenine phosphoribosyltransferase (APRT) activity in Trypanosoma brucei brucei: Only one of the two isoforms is kinetically active PLoS Negl Trop Dis. 2022 Feb 1;16(2):e0009926.
- Amundson SA, Fortunato JE, Liber HL. Heritable alterations at the adenine phosphoribosyltransferase (APRT) locus in human lymphoblastoid cell lines Mutat Res. 1992 Dec 16;284(2):287-95.
- Runolfsdottir HL, Palsson R, Agustsdottir IM, Indridason OS, Edvardsson VO. Kidney Disease in Adenine Phosphoribosyltransferase Deficiency Am J Kidney Dis. 2016 Mar;67(3):431-8.
- Kahan B, Held KR, DeMars R. The locus for human adenine phosphoribosyltransferase on chromosome no. 16 Genetics. 1974 Dec;78(4):1143-56.
