Hinokitiol Iron Chelator
| Catalog number: | B2014971 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 20 mg |
| Molecular Weight or Concentration: | 164.2 |
| Supplied as: | Solid |
| Applications: | molecular tool for various biochemical applications |
| Storage: | RT |
| Keywords: | 4-Isopropyltropolone |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Jin X, Zhang M, Lu J, Duan X, Chen J, Liu Y, Chang W, Lou H. Hinokitiol chelates intracellular iron to retard fungal growth by disturbing mitochondrial respiration J Adv Res. 2021 Jun 17;34:65-77.
- Abo Laban AI, El-Bassossy HM, Hassan NA. Hinokitiol produces vasodilation in aortae from normal and angiotensin II- induced hypertensive rats via endothelial-dependent and independent pathways Vascul Pharmacol. 2022 Oct;146:107092.
- Chelpuri Y, Pabbathi S, Alla GR, Yadala RK, Kamishetti M, Banothu AK, Boinepally R, Bharani KK, Khurana A. Tropolone derivative hinokitiol ameliorates cerulein-induced acute pancreatitis in mice Int Immunopharmacol. 2022 Aug;109:108915.
- Ni YJ, Huang ZN, Li HY, Lee CC, Tyan YC, Yang MH, Pangilinan CR, Wu LH, Chiang YC, Lee CH. Hinokitiol impedes tumor drug resistance by suppressing protein kinase B/mammalian targets of rapamycin axis J Cancer. 2022 Mar 14;13(6):1725-1733.
- Le CY, Ye YJ, Xu J, Li L, Feng XQ, Chen NP, Zhu BQ, Ding ZS, Qian CD. Hinokitiol Selectively Enhances the Antibacterial Activity of Tetracyclines against Staphylococcus aureus Microbiol Spectr. 2023 Mar 21;11(2):e0320522.
- Wang WK, Lin ST, Chang WW, Liu LW, Li TY, Kuo CY, Hsieh JL, Lee CH. Hinokitiol induces autophagy in murine breast and colorectal cancer cells Environ Toxicol. 2016 Jan;31(1):77-84.
- Oyama T, Ogawa H, Shirai Y, Abe H, Kamiya T, Abe T, Tanuma SI. Hinokitiol-induced decreases of tyrosinase and microphthalmia-associated transcription factor are mediated by the endoplasmic reticulum-associated degradation pathway in human melanoma cells Biochimie. 2022 Jan;192:13-21.
- Lin HC, Wang CC, Wu CF, Lin YH, Lee WC, Chen PJ, Chang YU, Su YC. Hinokitiol Inhibits the Viability of Oral Squamous Carcinoma Cells by Inducing Apoptosis and Autophagy Anticancer Res. 2023 Mar;43(3):1167-1173.
- Lu WJ, Lin KH, Tseng MF, Yuan KC, Huang HC, Sheu JR, Chen RJ. New therapeutic strategy of hinokitiol in haemorrhagic shock-induced liver injury J Cell Mol Med. 2019 Mar;23(3):1723-1734.








