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Citrullinated GRP78 Human Recombinant

Original price was: $118.40.Current price is: $81.24.

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SKU: PW14836851562 Category:

Citrullinated GRP78 Human Recombinant

Catalog number: B2017429
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 g
Molecular Weight or Concentration: 74.6 kDa
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -80C
Keywords: BiP, Endoplasmic Reticulum Lumenal Ca2+-Binding Protein GRP78, Glucose-Related Protein 78, Heat Shock Protein 5 (70 kDa), Hsp5 (70 kDa), Immunoglobulin Heavy Chain-Binding Protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um.

References

  • Azoury ME, Samassa F, Buitinga M, Nigi L, Brusco N, Callebaut A, Giraud M, Irla M, Lalanne AI, Carr A, Afonso G, Zhou Z, Brandao B, Colli ML, Sebastiani G, Dotta F, Nakayama M, Eizirik DL, You S, Pinto S, Mamula MJ, Verdier Y, Vinh J, Buus S, Mathieu C, Overbergh L, Mallone R. CD8(+) T Cells Variably Recognize Native Versus Citrullinated GRP78 Epitopes in Type 1 Diabetes Diabetes. 2021 Dec;70(12):2879-2891.
  • Brentville VA, Symonds P, Chua J, Skinner A, Daniels I, Cook KW, Koncarevic S, Martinez-Pinna R, Shah S, Choudhury RH, Vaghela P, Weston D, Al-Omari A, Davis J, Durrant LG. Citrullinated glucose-regulated protein 78 is a candidate target for melanoma immunotherapy Front Immunol. 2022 Dec 5;13:1066185.
  • Lu MC, Lai NS, Yu HC, Huang HB, Hsieh SC, Yu CL. Anti-citrullinated protein antibodies bind surface-expressed citrullinated Grp78 on monocyte/macrophages and stimulate tumor necrosis factor alpha production Arthritis Rheum. 2010 May;62(5):1213-23.
  • Gonzalez-Gronow M, Pizzo SV. Physiological Roles of the Autoantibodies to the 78-Kilodalton Glucose-Regulated Protein (GRP78) in Cancer and Autoimmune Diseases Biomedicines. 2022 May 24;10(6):1222.
  • Lu MC, Lai NS, Yin WY, Yu HC, Huang HB, Tung CH, Huang KY, Yu CL. Anti-citrullinated protein antibodies activated ERK1/2 and JNK mitogen-activated protein kinases via binding to surface-expressed citrullinated GRP78 on mononuclear cells J Clin Immunol. 2013 Apr;33(3):558-66.
  • Buitinga M, Callebaut A, Marques Cmara Sodr F, Crvecoeur I, Blahnik-Fagan G, Yang ML, Bugliani M, Arribas-Layton D, Marr M, Cook DP, Waelkens E, Mallone R, Piganelli JD, Marchetti P, Mamula MJ, Derua R, James EA, Mathieu C, Overbergh L. Inflammation-Induced Citrullinated Glucose-Regulated Protein 78 Elicits Immune Responses in Human Type 1 Diabetes Diabetes. 2018 Nov;67(11):2337-2348.
  • Rondas D, Crvecoeur I, DHertog W, Ferreira GB, Staes A, Garg AD, Eizirik DL, Agostinis P, Gevaert K, Overbergh L, Mathieu C. Citrullinated glucose-regulated protein 78 is an autoantigen in type 1 diabetes Diabetes. 2015 Feb;64(2):573-86.
  • Chi H, Hao W, Qi X, Zhang T, Dong Y, Gao H, Wei C, Shi W. A proteomic approach towards understanding the pathogenesis of Moorens ulcer Exp Eye Res. 2021 Apr;205:108509.
  • Shoda H, Fujio K, Shibuya M, Okamura T, Sumitomo S, Okamoto A, Sawada T, Yamamoto K. Detection of autoantibodies to citrullinated BiP in rheumatoid arthritis patients and pro-inflammatory role of citrullinated BiP in collagen-induced arthritis Arthritis Res Ther. 2011;13(6):R191.