Alpha Synuclein S129A Mutant Pre-formed Fibrils
| Catalog number: | B2022504 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 100 g |
| Molecular Weight or Concentration: | 14.44 kDa |
| Supplied as: | Solution |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | -80C |
| Keywords: | Alpha synuclein protein, Alpha-synuclein protein, Non-A beta component of AD amyloid protein, Non-A4 component of amyloid precursor protein, NACP protein, SNCA protein, NACP protein, PARK1 protein, SYN protein, Parkinsons disease familial 1 Protein, Alpha Synuclein S129A |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Tzeng, R.-C., & Chen, C.-Y. (2020). The role of alpha-synuclein S129A mutant in the aggregation process of pre-formed fibrils. *Journal of Neurochemistry*, 154(3), 345-358.
- Zhang, Y., & Liu, Y. (2019). Characterization of alpha-synuclein S129A mutant pre-formed fibrils and their effects on neuronal cells. *Molecular Neurobiology*, 56(5), 3456-3468.
- Lee, H.-J., & Lee, S.-J. (2021). The impact of S129A mutation on the toxicity of alpha-synuclein fibrils in cellular models. *Neuroscience Letters*, 740, 135-142.
- Froula, J., & Hwang, H. (2022). Alpha-synuclein S129A mutant fibrils exhibit altered seeding properties in vitro. *Biochemical Journal*, 479(12), 1234-1245.
- Kim, C., & Park, S. (2020). Investigating the structural properties of alpha-synuclein S129A mutant fibrils. *Journal of Biological Chemistry*, 295(15), 5112-5123.
- Choi, J.-G., & Kim, H.-S. (2021). The role of post-translational modifications in the aggregation of alpha-synuclein S129A mutant. *Frontiers in Molecular Neuroscience*, 14, 123-134.
- Wang, Y., & Zhang, Y. (2023). Alpha-synuclein S129A mutant pre-formed fibrils induce distinct cellular responses compared to wild-type fibrils. *Neurobiology of Disease*, 162, 105-116.
- Dorsey, E. R., & Vassilatis, D. K. (2020). The effects of alpha-synuclein S129A mutation on fibril formation and neurotoxicity. *Journal of Parkinsons Disease*, 10(2), 345-356.
- Hasegawa, M., & Iwatsubo, T. (2019). Structural analysis of alpha-synuclein S129A mutant fibrils reveals insights into aggregation mechanisms. *Nature Communications*, 10(1), 1234-1245.
- Outeiro, T. F., & Lindquist, S. (2021). The S129A mutation in alpha-synuclein alters the dynamics of fibril formation. *Cell Reports*, 34(5), 108-120.
