5-FAM Cadaverine

5-FAM Cadaverine Catalog B2011351 (5 mg)

5-FAM Cadaverine is a fluorescent amine-reactive labeling reagent comprising cadaverine conjugated to the 5-carboxyfluorescein (5-FAM) dye, offering robust and bright green fluorescence for biological labeling and detection applications. Supplied as a 5 mg lyophilized powder (Catalog B2011351), this biotechnology-grade reagent ensures high sensitivity and efficient conjugation to amine-bearing molecules such as proteins, peptides, and antibodiesmaking it ideal for fluorescence microscopy, flow cytometry, and advanced biochemical assays.

Manufactured with stringent purity standards and processed using ultrapure water and sterile filtration, 5-FAM Cadaverine delivers low background signals and high reproducibility. Its lyophilized format enables long-term stability at 20 C, supporting precise solubilization and dosing for experimental consistency. This reagent is truly versatile for conjugation protocols, and custom bulk options are available to meet the demands of scaling projects or longitudinal research.

Why researchers choose this product:

• Bright green 5-FAM fluorophore ideal for sensitive detection in imaging and flow cytometry
• Amine-reactive cadaverine linker enables straightforward biomolecular conjugation
• High biotech-grade purity minimizes nonspecific fluorescence and enhances reproducibility
• Lyophilized format ensures long-term stability and precise handling
• Bulk supply available to support large-scale labeling protocols and study consistency

Indication for Use:
This product is for Research Use Only (RUO). It is not intended for diagnostic, therapeutic, or clinical applications.

References:

• 1: Gibbs NM, Su SH, Lopez-Nieves S, Mann S, Alban C, Maeda HA, Masson PH. Cadaverine regulates biotin synthesis to modulate primary root growth in Arabidopsis Plant J. 2021 Sep;107(5):1283-1298.
• 2: Moon YM, Yang SY, Choi TR, Jung HR, Song HS, Han YH, Park HY, Bhatia SK, Gurav R, Park K, Kim JS, Yang YH. Enhanced production of cadaverine by the addition of hexadecyltrimethylammonium bromide to whole cell system with regeneration of pyridoxal-5-phosphate and ATP Enzyme Microb Technol. 2019 Aug;127:58-64.
• 3: Kim JH, Kim J, Kim HJ, Sathiyanarayanan G, Bhatia SK, Song HS, Choi YK, Kim YG, Park K, Yang YH. Biotransformation of pyridoxal 5-phosphate from pyridoxal by pyridoxal kinase (pdxY) to support cadaverine production in Escherichia coli Enzyme Microb Technol. 2017 Sep;104:9-15.
• 4: Verhage L. Smelly business Cadaverine modulates root growth by inhibiting biotin synthesis Plant J. 2021 Sep;107(5):1281-1282.
• 5: Brito LF, Irla M, Nrdal I, Le SB, Delpine B, Heux S, Brautaset T. Evaluation of Heterologous Biosynthetic Pathways for Methanol-Based 5-Aminovalerate Production by Thermophilic Bacillus methanolicus Front Bioeng Biotechnol. 2021 Jun 28;9:686319.
• 6: Han YH, Kim HJ, Choi TR, Song HS, Lee SM, Park SL, Lee HS, Cho JY, Bhatia SK, Gurav R, Park K, Yang YH. Improvement of cadaverine production in whole cell system with bakers yeast for cofactor regeneration Bioprocess Biosyst Eng. 2021 Apr;44(4):891-899.
• 7: Ikeda N, Miyamoto M, Adachi N, Nakano M, Tanaka T, Kondo A. Direct cadaverine production from cellobiose using -glucosidase displaying Escherichia coli AMB Express. 2013 Nov 8;3(1):67.
• 8: Rui J, You S, Zheng Y, Wang C, Gao Y, Zhang W, Qi W, Su R, He Z. High-efficiency and low-cost production of cadaverine from a permeabilized-cell bioconversion by a Lysine-induced engineered Escherichia coli Bioresour Technol. 2020 Apr;302:122844.
• 9: Wang X, Guo X, Wang J, Li H, He F, Xu S, Chen K, Ouyang P. Ameliorating end-product inhibition to improve cadaverine production in engineered Escherichia coli and its application in the synthesis of bio-based diisocyanates Synth Syst Biotechnol. 2021 Sep 14;6(4):243-253.
• 10: Wang J, Lu X, Ying H, Ma W, Xu S, Wang X, Chen K, Ouyang P. A Novel Process for Cadaverine Bio-Production Using a Consortium of Two Engineered Escherichia coli Front Microbiol. 2018 Jun 19;9:1312.